LOPIVASC FILM-COATED TABLET 5MG

CAUTION: Foods, Drugs, Devices, and Cosmetics Act prohibit dispensing without a prescription.

THIS IS A PRESCRIPTION DRUG. The contents of this page are provided for information purposes only and should not be a substitute for a professional medical advice or for self-medication. Consult your physician or pharmacist before administration and read all labels prior to use.

LOPIVASC FILM-COATED TABLET
ANTIHYPERTENSIVE
30 TABLETS PER BOX

Amlodipine Besilate          5 mg

INDICATIONS:

Amlodipine is a dihydropyridine calcium-channel blocker. It is a peripheral and coronary vasodilator but unlike the calcium-channel blockers Verapamil or Diltiazem, has little or no effect on caridac conduction and negative inotropic activity is rarely seen at therapeutic doses. Administration results primariy in vasodilatation, with reduced peripheral resistance, blood pressure, and afterload, increased coronary  blood flow, and a reflex increase in heart rate. This in turn results in an increase myocardial oxygen supply and cardiac output. It has no antiarrhythmic activity. Amlodipine maybe even more selective than Nifedipine for vascular smooth muscle. Most of the dihydropyridine calcium-channel blockers are chiral compounds used as racemic mixtures.

Amplodipine is used in the management of hypertension; in the prophylaxis of agina pectoris, particularly when a vasospastic element is present, as in Prizmental's agina, and in the treatment of Raynand's syndrome.

DOSAGE AND ADMINISTRATION:

Hypertension: usual initial dose is 5 mg once daily. Increased if necessary to 10 mg once daily or as precribed by the physician.

Similar doses are given in the treatment of stable angina and Prinzmetal's angina or as prescribed by the physician.

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